Evaṃ yathānikkhittāya desanāya padaṭṭhānavasena atthaṃ niddhāretvā idāni taṃ sabhāgavisabhāgadhammavasena āvaṭṭetukāmo tassa bhūmiṃ dassetuṃ ‘‘ ayuñjantānaṃ vā sattānaṃ yoge yuñjantānaṃ vā ārambho ’’ tiādimāha. Tassattho – yoge bhāvanāyaṃ taṃ ayuñjantānaṃ vā sattānaṃ aparipakkañāṇānaṃ vāsanābhāgena āyatiṃ vijānanatthaṃ ayaṃ desanārambho yuñjantānaṃ vā paripakkañāṇānanti. (N-A, p105)

So pamādo duvidhoti yena pamādena bhāvanaṃ nānuyuñjanti, so pamādo attano kāraṇabhedena duvidho.(N-A, 105)

Being concealed by unknowing (delusion), with negligence, one does not know the base/thing should be known as five aggregates which have the nature of arising and perishing. This negligence is known as having the avijja (concealment) as root cause.